Teacrine Replaces Caffeine

by Dr. Jacob Wilson, Ph.D., CSCS*D

January 24, 2018


There is a new specialty ingredient on the market called TeaCrine®. TeaCrine® is named after the active compound Kuchu tea plant called Theacrine. It is similar to caffeine in that it is an alkaloid, a scientific word for the active compound in a supplement, but its effects have been shown to be more beneficial than caffeine. When isolated Theacrine is taken alone, it can increase focus, energy, and motivation while simultaneously decreasing fatigue (Taylor et al., 2016; Lopez et al., 2016).

Theacrine Cognitive Benefits

The difference between theacrine and caffeine is that you can take it in smaller doses and achieve an equal if not greater stimulatory effect. Basically, that means theacrine will give you the same focus and energy as caffeine in a smaller dose. Another awesome thing about theacrine is it is an anti-adaptogenic, which means that you do not adapt to it as quickly as you do caffeine. This has been shown in a few clinical trials where participants supplementing with TeaCrine® felt the exact same effects in the last dose compared to the first.


This clinical trial that I spoke of had three separate groups. One consuming caffeine and TeaCrine®, one consuming strictly caffeine, and the last consuming nothing at all. Throughout the study each participant was a part of each group one time. The researchers looked at various different variables in regard to mood, energy, and attentiveness. And after the supplementation period they found that when the participants supplemented with TeaCrine® and caffeine they had higher feelings of attentiveness, alertness, focus, and energy over both groups! While a lot more research needs to be done on TeaCrine it definitely shows promise (Kuhman et al., 2015).

Theacrine and Exercise


Another interesting attribute to TeaCrine is that it not only increases focus and energy, it has also been shown to increase your willingness to exercise and desire to train. When you train our body’s main energy source ATP is broken down into adenosine. Adenosine signals the body that you are fatigued and low on energy by binding to landing docks called receptors in the brain. Theacrine works by blocking adenosine receptors. This causes the stimulatory effects that increase energy and alertness. Theacrine has also been shown to increase dopamine. What is beneficial about increased dopamine is the fact that it increases the “reward center” of the brain causing an overall increase in well-being. Therefore, it can not only increase focus but also increase the reward center in the brain causing the pleasure response. This can further enhance the energy and alertness effects. There is even evidence showing that theacrine can be beneficial for libido. If you’re looking for a well-rounded, all-in-one product. Then you found it in TeaCrine®.

Theacrine Dosing

The dosing on TeaCrine® varies depending on if you are stacking it with other stimulants or nootropics. TeaCrine® has been recognized as safe by the Informed Choice and Informed Sport, WADA, and the NCAA, therefore college and pro athletes are able to take this product without wondering if they are going to fail a drug test. Lastly, doses up to 400mg/day have been shown to be safe in clinical trials. However, if you’re using TeaCrine® as stand-alone product, 100-200mg/day will do the trick. If you are using it in combination with caffeine, I would recommend 50-100mg of both to start. From there, you can increase caffeine to 100-200mg and theacrine to 100-150mg per day.


Since the release of TeaCrine® many companies have been putting it in their pre-workout and fat burners because it has such promising effects. From other bodies of research, TeaCrine® has been shown to give consistent results in regards to energy, mood, and overall alertness with the benefits of smaller doses and little to no adaptive properties. You may find theacrine labeled as TeaCrine® on various products because this is its patented name.